Fri May 13 2022

53 articles - From Friday May 06 2022 to Friday May 13 2022

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Guidelines

Guidelines, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews


Original articles

RCT, clinical trials, retrospective studies, etc…

Ann Intern Med

Diabetes Screening by Race and Ethnicity in the United States: Equivalent Body Mass Index and Age Thresholds.

Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology.

Pubmed   Journal   ReadQx 

Lancet

Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial.

Interpretation In secondary prevention, the Mediterranean diet was superior to the low-fat diet in preventing major cardiovascular events. Our results are relevant to clinical practice, supporting the use of the Mediterranean diet in secondary prevention. Funding Fundacion Patrimonio Comunal Olivarero; Fundacion Centro para la Excelencia en Investigacion sobre Aceite de Oliva y Salud; local, regional, and national Spanish Governments; European Union.

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Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses.

Remdesivir has no significant effect on patients with COVID-19 who are already being ventilated. Among other hospitalised patients, it has a small effect against death or progression to ventilation (or both). WHO.

Pubmed   Journal   ReadQx   PMC

N Engl J Med

Capsid Inhibition with Lenacapavir in Multidrug-Resistant HIV-1 Infection.

In patients with multidrug-resistant HIV-1 infection, those who received lenacapavir had a greater reduction from baseline in viral load than those who received placebo. (Funded by Gilead Sciences; CAPELLA ClinicalTrials.gov number, NCT04150068.).

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Evaluation of mRNA-1273 Covid-19 Vaccine in Children 6 to 11 Years of Age.

Two 50-µg doses of the mRNA-1273 vaccine were found to be safe and effective in inducing immune responses and preventing Covid-19 in children 6 to 11 years of age; these responses were noninferior to those in young adults. (Funded by the Biomedical Advanced Research and Development Authority and the National Institute of Allergy and Infectious Diseases; KidCOVE ClinicalTrials.gov number, NCT04796896.).

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Ann Intern Med

Care of the Patient After Metabolic and Bariatric Surgery.

Patients require ongoing monitoring of their physical and mental health for lasting success. Internists, particularly primary care clinicians, are in an ideal position to monitor for nonserious complications in the short and long term, adjust management of chronic diseases accordingly, and monitor for mental health changes. This article reviews key issues that internists should be aware of for supporting patients' health in the short and long term after MBS.

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Lancet

Chronic obstructive pulmonary disease.

Although few novel treatments have been approved for COPD in the past 5 years, advances have been made in targeting existing therapies to specific subpopulations using new biomarker-based strategies. Additionally, COVID-19 has undeniably affected individuals with COPD, who are not only at higher risk for severe disease manifestations than healthy individuals but also negatively affected by interruptions in health-care delivery and social isolation. This Seminar reviews COPD with an emphasis on recent advances in epidemiology, pathophysiology, imaging, diagnosis, and treatment.

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COVID-19: the next phase and beyond.

Pubmed   Journal   ReadQx   PMC

Offline: Gradually, then suddenly.

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Suicide and self-harm.

Several clinical and public health interventions show promise, although our understanding of their effectiveness has largely originated from high-income countries. Attempting to predict suicide is unlikely to be helpful. Intervention and prevention must include both a clinical and community focus, and every health professional has a crucial part to play.

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N Engl J Med

Audio Interview: Forecasting the Future of Covid.

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Lenacapavir for HIV-1 - Potential Promise of a Long-Acting Antiretroviral Drug.

Pubmed   Journal   ReadQx 


Letters&Replies

Letters to the editors and authors’ replies

Lancet

Allocated but not treated: the silent 16% - Authors' reply.

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Allocated but not treated: the silent 16.

Pubmed   Journal   ReadQx   PMC

An urgent plea for surgical care in Lebanon.

Pubmed   Journal   ReadQx 

Counting the global COVID-19 dead.

Pubmed   Journal   ReadQx   PMC

COVID-19 and inter-generational solidarity.

Pubmed   Journal   ReadQx   PMC

Shanghai's life-saving efforts against the current omicron wave of the COVID-19 pandemic.

Pubmed   Journal   ReadQx   PMC

N Engl J Med

BNT162b2 Protection against the Omicron Variant in Children and Adolescents.

Pubmed   Journal   ReadQx 

BNT162b2 Protection against the Omicron Variant in Children and Adolescents. Reply.

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Fractional Flow Reserve-Guided PCI as Compared with Coronary Bypass Surgery.

Pubmed   Journal   ReadQx 

Fractional Flow Reserve-Guided PCI as Compared with Coronary Bypass Surgery.

Pubmed   Journal   ReadQx 

Fractional Flow Reserve-Guided PCI as Compared with Coronary Bypass Surgery.

Pubmed   Journal   ReadQx 

Fractional Flow Reserve-Guided PCI as Compared with Coronary Bypass Surgery.

Pubmed   Journal   ReadQx 

Fractional Flow Reserve-Guided PCI as Compared with Coronary Bypass Surgery. Reply.

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Medical Conditions and High-Altitude Travel.

Pubmed   Journal   ReadQx 

Medical Conditions and High-Altitude Travel. Reply.

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Nivolumab with or without Relatlimab in Untreated Advanced Melanoma.

Pubmed   Journal   ReadQx 

Nivolumab with or without Relatlimab in Untreated Advanced Melanoma. Reply.

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Tricuspid Repair in Patients with Degenerative Mitral Regurgitation.

Pubmed   Journal   ReadQx 

Tricuspid Repair in Patients with Degenerative Mitral Regurgitation.

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Tricuspid Repair in Patients with Degenerative Mitral Regurgitation.

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Tricuspid Repair in Patients with Degenerative Mitral Regurgitation. Reply.

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Others

all remaining publications eg case reports, images of the month, etc…

Ann Intern Med

Bias Against the Willfully Unvaccinated.

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Diabetes Screening: Different Thresholds for Different Racial/Ethnic Groups.

Pubmed   Journal   ReadQx 

Summary for Patients: Screening for Diabetes by Race and Ethnicity in the United States.

Pubmed   Journal   ReadQx 

Web Exclusive. Annals Graphic Medicine - More Than Skin Deep.

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Lancet

Child health and wellbeing dashboards: accountability for children's rights.

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Closing the global vaccine equity gap: equitably distributed manufacturing.

Pubmed   Journal   ReadQx   PMC

Ebola outbreak in DR Congo.

Pubmed   Journal   ReadQx 

Healing the Amazon.

Pubmed   Journal   ReadQx 

Hunt begins for the cause of acute hepatitis cases.

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Imagining technologies for disability futures.

Pubmed   Journal   ReadQx 

Improving health in immigration detention and promoting alternatives to detention.

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Pre-eclampsia with paradoxical polyuria: diabetes insipidus in pregnancy.

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Siobhan Wescott: steadfast advocate for Native American health.

Pubmed   Journal   ReadQx 

When and which patients should receive remdesivir?

Pubmed   Journal   ReadQx   PMC

N Engl J Med

Case 14-2022: A 57-Year-Old Man with Chylous Ascites.

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Climate Change in the Supreme Court.

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Emphysematous Aortitis.

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Navigating Loss of Abortion Services - A Large Academic Medical Center Prepares for the Overturn of Roe v. Wade.

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Retinal Hemorrhages in Leukemia.

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Supporting Innovation in Medicaid Policy - Interventions to Increase Adoption of RCTs.

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